THE ACE I/D GENE POLYMORPHISM AND PHYSICAL PERFORMANCE IN A NON-ELITE FEMALE COHORT
F. Sırrı ÇAM1, Muzaffer ÇOLAKOĞLU2, Şule ÇOLAKOĞLU3,Afig BERDELİ4
1Celal Bayar Üniversitesi Tıp Fakültesi Tıbbi Biyoloji ve Genetik AD, Manisa
2Ege Üniversitesi Beden Eğitimi ve Spor Yüksek Okulu, İzmir
3Celal Bayar Üniversitesi Beden Eğitimi ve Spor Yüksek Okulu, Manisa
4Ege Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları AD, İzmir
Keywords: Genetics, endurance performance, insertion/deletion, sprint, exercise
I/D polymorphism of the ACE gene may be associated with better endurance performance and a stronger response to exercise training. The aim of this study was to investigate the association between ACE gene polymorphism and athletic performance in a homogeneous female cohort. Thirty-two female non-elite Caucasian Turkish athletes with similar training backgrounds for at least six months were studied for ACE gene polymorphisms using PCR analysis. Their sixty-meter sprint and middle distance running test performances were evaluated. The distribution of the ACE I/D genotypes was found to be 34.4%, 37.5% and 28.1% for II, ID and DD polymorphisms respectively, in the study cohort. There were no significant differences amongst ACE genotype groups with respect to their sprint (χ2: 3.261; p=0.196) or middle distance (χ2: 0.396; p=0.820) performances. No significant relationship was found between ACE genotypes and sprint or endurance performances in non-elite female athletes. Studies with larger cohorts may produce significant relationships.